University of East London researchers found allicin treated even the most antibiotic-resistant strains of the infection.
MRSA (Methecillin-resistant Staphylococcus aureus) causes an estimated 2,000 deaths in UK hospitals each year.
Researchers
are now testing allicin products in a six-month study. Dr Ron Cutler
and his team discovered the effectiveness of allicin in laboratory
tests five years ago.
They found it can cure MRSA within weeks.
It
is even effective against the newer strains which cannot be treated by
the "last line of defence" antibiotics Vancomycin and Glycopeptides.
Fatal infections
The
team have developed a nasal cream, pills and soaps. Initial trials have
proved effective, so researchers will now test them in a six-month
study of 200 volunteers including healthcare workers and patients.
The
scientists hope the products will be used by people working in
hospitals so they can prevent MRSA being passed on to patients, as well
as the patients themselves.
MRSA organisms
can live harmlessly in humans, carried in the nasal passages and on the
skin, but they can cause fatal infections in immune-suppressed
patients, the elderly, the young and those with surgical implants.
Dr
Cutler told BBC News Online: "My aim would be to firstly work to try
and reduce the carriage of MRSA amongst healthcare workers. But we
would also hope to use allicin treatments for patients themselves."
He
added: "The trials we have conducted so far show that this formulation
is highly effective against MRSA, and it could save many lives.
"MRSA
is causing a genuine crisis in our hospital system in Britain and
worldwide. Antibiotics are increasingly ineffective, but we do have a
powerful natural ally.
"Plant compounds have evolved over
millions of years as chemical defense agents against infection. Garlic
has been used in medicine for centuries, and it should be no surprise
that it is effective against this very modern infection."
'Incredibly painful'
Deborah Brown, 34, from Rainham in Kent, contracted MRSA after a major spinal operation in November 2000.
Painful wounds on her spine failed to heal for two years, despite using the antibiotics and creams currently available.
But within two months of using the allicin creams and pills, her MRSA had virtually cleared and the wounds had begun to heal.
She said: "The effect of the treatment was dramatic - I am making a good recovery - but it was really awful at the time.
"Having
weeping wounds on my back that never healed was incredibly painful and
I became increasingly depressed as the MRSA didn't respond to repeated
courses of antibiotics.
"If my case helps to show that allicin works against MRSA then I am glad that something good might come of it."
The research is to be published in the Journal of Biomedical Science next year.
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